Menu
With advances in modern medicine, it’s now possible to use predictive genetic testing to look for gene mutations that may indicate you’re more likely to develop a type of cancer, including breast cancer. Premal Sanghavi, MD, FACS, offers genetic testing at her practice in downtown Los Angeles and Glendale, California, Premal Sanghavi MD, Inc. To learn more, call the office or schedule an appointment online today.
Genes are pieces of DNA inside cells that tell the cell how to make the proteins that your body needs to function. Changes in genes, called mutations, play an important role in the development of cancer. Predictive genetic testing is testing used to look for mutations in the genes that might put a person at a high risk of getting breast cancer.
Genetic testing is intended for patients to know if their breast cancer or family history of breast cancer is due to an inherited gene mutation. In the United States, 5-10 percent of breast cancers are linked to an inherited gene.
BRCA1 and BRCA2 are the most commonly associated mutated genes associated with breast cancer. In addition to mutations in BRCA1 and BRCA2, mutations in the following genes can increase your risk of breast cancer:
ATM
CDH1
CHEK2
NBN
NF1
PALB2
PTEN
STK11
TP53 (p53)
BRCA1 and BRCA2 are also linked to ovarian cancer.
Indications you may be a good candidate for genetic testing include:
Age onset of breast cancer is 50 or younger
Triple negative tumor (ER-, PR-, and HER2-) and being 60 or younger
Ashkenazi Jewish heritage and breast cancer at any age
Two or more primary breast cancers
First-degree relative with breast cancer who’s 50 or younger
Two relatives on the same side of the family with breast cancer and/or pancreatic cancer
Family or personal history of ovarian cancer, fallopian cancer, or primary peritoneal cancer
Male breast cancer
Known mutation carrier in the family
Find out if you can benefit from genetic testing to find out if you’re at an elevated risk of developing breast cancer. To talk to a skilled provider experienced in genetic testing, call Premal Sanghavi MD, Inc. in Los Angeles or Glendale, California, or schedule an appointment using the online booking feature today
The diagnosis of breast cancer is a life-changing experience. Not only does it bring you face to face with your mortality, but surgical…
Lumpectomy refers to a procedure that removes the tumor from the breast with a rim of normal tissue breast around it.
A sentinel lymph node is the first gland that filters fluid draining from the breast. Since the sentinel node is the first lymph node to filter lymphatic fluid from the breast…
Intraoperative radiation therapy for breast cancer can deliver a targeted radiation dose to a tumor bed during breast cancer surgery…
Oncoplastic breast surgery combines the principles of breast cancer and plastic surgery techniques.
With advances in modern medicine, it’s now possible to use predictive genetic testing to look for gene mutations…
A breast biopsy checks for the presence of cancer, so it’s especially important that a highly skilled and experienced…
Combining a mastectomy and breast reconstruction can help you feel more like yourself again.
You may have heard of the numerous benefits of a 3D mammogram, including its ability to find smaller cancers…
© Copyright 2024 premalsanghavimd | Website design and development by NXT GEN WEB